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Patients with long COVID-19—where the effects of an initial COVID infection last more than 12 weeks—had lower levels of 25(OH) vitamin D than other patients who survived COVID-19, in a retrospective, case-matched study.

The lower levels of vitamin D in patients with long COVID were most notable in those with brain fog.

These findings, by Luigi di Filippo, MD, and colleagues, were recently presented at the European Congress of Endocrinology (ECE) in Istanbul, Turkey, and published in the Journal of Clinical Endocrinology & Metabolism.

"Our data suggest that vitamin D levels should be evaluated in COVID-19 patients after hospital discharge," write the researchers from San Raffaele Hospital, Milan, Italy.

"The role of vitamin D supplementation as a preventive strategy of COVID-19 sequelae should be tested in randomized controlled trials," they urge.

The researchers also stress that this was a controlled study in a homogeneous population, it included multiple signs and symptoms of long COVID, and it had a longer follow-up than most previous studies (6 vs 3 months). Head over to Medscape to read the full story.